Article
The use of whole-genome sequencing in cluster investigation of a multidrug-resistant tuberculosis outbreak.
The European respiratory journal - 1 Jun 2018
Lalor Maeve K, Casali Nicola, Walker Timothy M, Anderson Laura F, Davidson Jennifer A, Ratna Natasha, Mullarkey Cathy, Gent Mike, Foster Kirsty, Brown Tim, Magee John, Barrett Anne, Crook Derrick W, Drobniewski Francis, Thomas H Lucy, Abubakar Ibrahim
Abstract excerpt
We used whole-genome sequencing (WGS) to delineate transmission networks and investigate the benefits of WGS during cluster investigation.We included clustered cases of multidrug-resistant (MDR) tuberculosis (TB)/extensively drug-resistant (XDR) TB linked by mycobacterial interspersed repetitive unit variable tandem repeat (MIRU-VNTR) strain typing or epidemiological information in the national cluster B1006,...
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