Article
Whole-genome sequencing to detect recent transmission of Mycobacterium tuberculosis in settings with a high burden of tuberculosis.
Tuberculosis (Edinburgh, Scotland) - 1 Jul 2014
Luo Tao, Yang Chongguang, Peng Ying, Lu Liping, Sun Guomei, Wu Jie, Jin Xiaoping, Hong Jianjun, Li Fabin, Mei Jian, DeRiemer Kathryn, Gao Qian
Abstract excerpt
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been used to trace the transmission of M. tuberculosis, the causative agent of tuberculosis (TB). Previously published studies using WGS were conducted in developed countries with a low TB burden. We sought to evaluate the relative usefulness of traditional VNTR and SNP typing methods, WGS and epidemiological investigations to study the recent...
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