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Article

Define SNP thresholds for delineation of tuberculosis transmissions using whole-genome sequencing.

Microbiology spectrum - 6 Aug 2024

Xiao Yu-Xin, Chan Tai-Hua, Liu Kuang-Hung, Jou Ruwen

Abstract excerpt

For facilitating tuberculosis (TB) control, we used a whole-genome sequencing (WGS)-based approach to delineate transmission networks in a country with an intermediate burden of TB. A cluster was defined as Mycobacterium tuberculosis isolates with identical genotypes, and an outbreak was defined as clustered cases with epidemiological links (epi-links). To refine a cluster predefined using space oligonucleotide...

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Identifiers

PMID: 38916321
DOI: 10.1128/spectrum.00418-24
PMCID: PMC11302064

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C2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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