Article
Effects of high-fat diet and AMP-activated protein kinase modulation on the regulation of whole-body lipid metabolism.
Journal of lipid research - 1 Jul 2018
Schönke Milena, Massart Julie, Zierath Juleen R
Abstract excerpt
Metabolic flexibility, the capacity to adapt to fuel availability for energy production, is crucial for maintaining whole-body energy homeostasis. An inability to adequately promote FA utilization is associated with lipid accumulation in peripheral tissues and contributes to the development of insulin resistance. In vivo assays to quantify whole-body lipid oxidation in mouse models of insulin resistance are...
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