Article
A review of standardized metabolic phenotyping of animal models.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2014
Rozman Jan, Klingenspor Martin, Hrabě de Angelis Martin
Abstract excerpt
Metabolic phenotyping of genetically modified animals aims to detect new candidate genes and related metabolic pathways that result in dysfunctional energy balance regulation and predispose for diseases such as obesity or type 2 diabetes mellitus. In this review, we provide a comprehensive overview on the technologies available to monitor energy flux (food uptake, bomb calorimetry of feces and food, and indirect...
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