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Article

Identifying static and kinetic lipid phenotypes by high resolution UPLC-MS: unraveling diet-induced changes in lipid homeostasis by coupling metabolomics and fluxomics.

Journal of proteome research - 2 Sept 2011

Castro-Perez Jose M, Roddy Thomas P, Shah Vinit, McLaren David G, Wang Sheng-Ping, Jensen Kristian, Vreeken Rob J, Hankemeier Thomas, Johns Douglas G, Previs Stephen F, Hubbard Brian K

Abstract excerpt

A novel method to differentiate diet-induced alterations in plasma lipid phenotypes "static (concentration of lipids) and kinetic (endogenous production, e.g., denovo lipogenesis)" was employed. C57Bl6 mice were randomized into 2 groups and fed either a high-carbohydrate, low-fat (HC) or a carbohydrate-free, high-fat diet (HF) diet for 13 days; D(2)O was administered via intraperitoneal injection and then adding...

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PMID: 21744776
DOI: 10.1021/pr200480g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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