Article
Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation.
Circulation. Cardiovascular imaging - 1 Mar 2018
Panagia Marcello, Chen Howard H, Croteau Dominique, Iris Chen Yin-Ching, Ran Chongzhao, Luptak Ivan, Josephson Lee, Colucci Wilson S, Sosnovik David E
Abstract excerpt
BACKGROUND: Substrate utilization in tissues with high energetic requirements could play an important role in cardiometabolic disease. Current techniques to assess energetics are limited by high cost, low throughput, and the inability to resolve multiple readouts simultaneously. Consequently, we aimed to develop a multiplexed optical imaging platform to simultaneously assess energetics in multiple organs in a...
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