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Article

SLCO1B1 genetic variation and hormone therapy in menopausal women.

Menopause (New York, N.Y.) - 1 Aug 2018

Moyer Ann M, de Andrade Mariza, Faubion Stephanie S, Kapoor Ekta, Dudenkov Tanda, Weinshilboum Richard M, Miller Virginia M

Abstract excerpt

OBJECTIVE: Response to menopausal hormone therapy (MHT) shows individual variation. SLCO1B1 encodes the OATP1B1 transporter expressed in the liver that transports many endogenous substances, including estrone sulfate, from the blood into hepatocytes. This study evaluated the relationship between genetic variation in SLCO1B1 and response to MHT in women enrolled in the Kronos Early Estrogen Prevention Study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29738412
DOI: 10.1097/GME.0000000000001109
PMCID: PMC6092108

Variants

rs4149056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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