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Article

Human estrogen sulfotransferase (SULT1E1) pharmacogenomics: gene resequencing and functional genomics.

British journal of pharmacology - 1 Aug 2003

Adjei Araba A, Thomae Bianca A, Prondzinski Janel L, Eckloff Bruce W, Wieben Eric D, Weinshilboum Richard M

Abstract excerpt

1. Estrogens are used as drugs and estrogen exposure is a risk factor for hormone-dependent diseases such as breast cancer. Sulfate conjugation is an important pathway for estrogen metabolism. The sulfotransferase (SULT) enzyme SULT1E1 has the lowest K(m) values for estrogens and catecholestrogen...

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Identifiers

PMID: 12922923
DOI: 10.1038/sj.bjp.0705369
PMCID: PMC1573968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12922923-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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