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Article

Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism.

Endocrinology - 1 Sept 2008

van der Deure Wendy M, Friesema Edith C H, de Jong Frank Jan, de Rijke Yolanda B, de Jong Frank H, Uitterlinden André G, Breteler Monique M B, Peeters Robin P, Visser Theo J

Abstract excerpt

Sulfation is an important pathway in the metabolism of thyroid hormone and estrogens. Sulfation of estrogens is reversible by estrogen sulfatase, but sulfation of thyroid hormone accelerates its degradation by the type 1 deiodinase in liver. Organic anion transporters (OATPs) are capable of trans...

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Identifiers

PMID: 18499754
DOI: 10.1210/en.2008-0169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18499754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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