Article
Effect of hormone metabolism genotypes on steroid hormone levels and menopausal symptoms in a prospective population-based cohort of women experiencing the menopausal transition.
Menopause (New York, N.Y.) - 1 Jan 2000
Rebbeck Timothy R, Su H Irene, Sammel Mary D, Lin Hui, Tran Teo V, Gracia Clarisa R, Freeman Ellen W
Abstract excerpt
OBJECTIVE: This study evaluated whether genes involved in the metabolism of steroid hormones are associated with hormone levels or menopausal symptoms. METHODS: We used a population-based prospective sample of 436 African American (AA) and European American (EA) women who were premenopausal at enrollment and were followed longitudinally through menopause. We evaluated the relationship between steroid hormone...
Topics
- Adult
- Black or African American
- Arylsulfotransferase
- Catechol O-Methyltransferase
- Cytochrome P-450 Enzyme System
- Depression
- Female
- Gonadal Steroid Hormones
- Hot Flashes
- Humans