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Article

XRCC3 Thr241Met polymorphism and risk of acute myeloid leukemia in a Romanian population.

Gene - 10 Sept 2013

Bănescu Claudia, Tilinca Mariana, Benedek Erzsebeth Lazar, Demian Smaranda, Macarie Ioan, Duicu Carmen, Dobreanu Minodora

Abstract excerpt

BACKGROUND: DNA repair systems have a critical role in maintaining the genome integrity and stability. DNA repair gene polymorphisms may influence the capacity to repair DNA damage, and thus lead to an increased cancer susceptibility. X-ray repair cross-complementing groups 3 (XRCC3), a DNA repair gene, may be involved in acute myeloid leukemia susceptibility. The objective of the current study was to investigate...

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Identifiers

PMID: 23747401
DOI: 10.1016/j.gene.2013.05.054

Genes

XRCC3

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