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Article

Analysis of DNA repair gene polymorphisms in glioblastoma.

Gene - 15 Feb 2014

Rodriguez-Hernandez Irene, Perdomo Sandra, Santos-Briz Angel, Garcia Juan Luis, Gomez-Moreta Juan Antonio, Cruz Juan Jesus, Gonzalez-Sarmiento Rogelio

Abstract excerpt

BACKGROUND: Glioblastoma is the most common and aggressive primary brain tumor in adults. Despite several factors such as ionizing radiation exposure or rare genetic syndromes have been associated with the development of glioblastoma, no underlying cause has been identified for the majority of cases. We thus aimed to investigate the role of DNA repair polymorphisms in modulating glioblastoma risk. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24325908
DOI: 10.1016/j.gene.2013.11.077

Genes

ERCC2
ERCC1
MLH1
APEX1
ERCC6
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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