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Article

Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1.

The Journal of cell biology - 2 Jul 2018

Schiklenk Christoph, Petrova Boryana, Kschonsak Marc, Hassler Markus, Klein Carlo, Gibson Toby J, Haering Christian H

Abstract excerpt

Although the formation of rod-shaped chromosomes is vital for the correct segregation of eukaryotic genomes during cell divisions, the molecular mechanisms that control the chromosome condensation process have remained largely unknown. Here, we identify the C2H2 zinc-finger transcription factor Zas1 as a key regulator of mitotic condensation dynamics in a quantitative live-cell microscopy screen of the fission...

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Identifiers

PMID: 29735745
DOI: 10.1083/jcb.201711097
PMCID: PMC6028546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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