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Article

Trans-ethnic study design approaches for fine-mapping.

European journal of human genetics : EJHG - 1 Aug 2016

Asimit Jennifer L, Hatzikotoulas Konstantinos, McCarthy Mark, Morris Andrew P, Zeggini Eleftheria

Abstract excerpt

Studies that traverse ancestrally diverse populations may increase power to detect novel loci and improve fine-mapping resolution of causal variants by leveraging linkage disequilibrium differences between ethnic groups. The inclusion of African ancestry samples may yield further improvements because of low linkage disequilibrium and high genetic heterogeneity. We investigate the fine-mapping resolution of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26839038
DOI: 10.1038/ejhg.2016.1
PMCID: PMC4856879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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