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Article

VarExp: estimating variance explained by genome-wide GxE summary statistics.

Bioinformatics (Oxford, England) - 1 Oct 2018

Laville Vincent, Bentley Amy R, Privé Florian, Zhu Xiaofeng, Gauderman Jim, Winkler Thomas W, Province Mike, Rao D C, Aschard Hugues

Abstract excerpt

Summary: Many genome-wide association studies and genome-wide screening for gene-environment (GxE) interactions have been performed to elucidate the underlying mechanisms of human traits and diseases. When the analyzed outcome is quantitative, the overall contribution of identified genetic variants to the outcome is often expressed as the percentage of phenotypic variance explained. This is commonly done using...

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PMID: 29726908
DOI: 10.1093/bioinformatics/bty379
PMCID: PMC6157079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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