Article
Conservation of the separase regulatory domain.
Biology direct - 27 Apr 2018
Melesse Michael, Bembenek Joshua N, Zhulin Igor B
Abstract excerpt
ᅟ: We report a protein sequence analysis of the cell cycle regulatory protease, separase. The sequence and structural conservation of the C-terminal protease domain has long been recognized, whereas the N-terminal regulatory domain of separase was reported to lack detectable sequence similarity. Here we reveal significant sequence conservation of the separase regulatory domain and report a discovery of a cysteine...
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