Article
A look at the Caenorhabditis elegans Kex2/Subtilisin-like proprotein convertase family.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jun 2000
Thacker C, Rose A M
Abstract excerpt
Significant advances have recently been made in our understanding of the mechanisms of activation of proteins that require processing. Often this involves endoproteolytic cleavage of precursor forms at basic residues, and is carried out by a group of serine endoproteinases, termed the proprotein convertases. In mammals, seven different convertases have been identified to date. These act in both the regulated...
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