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Article

Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2018

Laetsch Theodore W, Roy Angshumoy, Xu Lin, Black Jennifer O, Coffin Cheryl M, Chi Yueh-Yun, Tian Jing, Spunt Sheri L, Hawkins Douglas S, Bridge Julia A, Parsons D Williams, Skapek Stephen X

Abstract excerpt

Purpose: A comprehensive analysis of the genomics of undifferentiated sarcomas (UDS) is lacking. We analyzed copy-number alterations and fusion status in patients with UDS prospectively treated on Children's Oncology Group protocol ARST0332.Experimental Design: Copy-number alterations were assessed by OncoScan FFPE Express on 32 UDS. Whole-exome and transcriptome libraries from eight tumors with sufficient...

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Identifiers

PMID: 29691299
DOI: 10.1158/1078-0432.CCR-18-0672
PMCID: PMC6335968

Genes

FGF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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