Article
Mapping Genomic Heterogeneity in Pediatric and Adolescent-Young Adult Sarcomas: Insights from the Italian SAR-GEN2016 and SAR-GEN_ITA Prospective Multicenter Trials.
Cancer research communications - 1 Apr 2026
Tirtei Elisa, Difilippo Valeria, Divincenzo Federico, Asaftei Sebastian Dorin, Ratto Nicola, Piana Raimondo, Pellegrino Pietro, Linari Alessandra, Papotti Mauro, Mareschi Katia, Parlato Caterina, Guarrera Simonetta, Minucci Saverio, Rabusin Marco, Manzitti Carla, Prete Arcangelo, Mercolini Federico, Luksch Roberto, Meazza Cristina, Parafioriti Antonina, Tamburini Angela, Coccoli Luca, Mura Rosamaria, Zecca Marco, Palmerini Emanuela, Ibrahim Toni, Peirone Serena, Penolazzi Linda, De Luna Elvira, Cagnazzo Celeste, Bombaci Sabrina, Ferrero Ivana, Niclot Alessia Giovanna Santa Banche, Proto Camilla Francesca, Spadea Manuela, Quarello Paola, Marini Elena, Gizzi Katiuscia, Fenoglio Beatrice, Livellara Virginia, Di Gangi Alessandro, Puma Nadia, Sironi Giovanna, Di Bernardo Andrea, Cereda Matteo, Fagioli Franca
Abstract excerpt
Sarcomas in pediatric and adolescent-young adult (AYA) populations represent rare and biologically heterogeneous tumors with complex genetic underpinnings. Genomic profiling reveals subtype-specific alterations and therapeutic targets. Such tumors still represent an unmet clinical need due to limited treatment options and poorer outcomes, especially in advanced stages. Here, we present the SAR-GEN2016 and...
Topics
Join the communities discussing this publication.