Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative Genomic Profiling of Pediatric Solid Tumors Reveals Clinically Relevant Variants and Chromosomal Arm Aneuploidies Signatures.

Cancer medicine - 1 Mar 2026

Yan Bingxiao, Wang Jinhu, Xiong Jieni, Liu Shuangai, Tang Yinbing, He Ziqi, Yan Hujin, Guo Bize, Chen Chen, Zhang Yijie, Zhu Qinfang, Cai Jiabin, He Min, Wu Xuan, Mao Junqing, Zhang Lifeng, Gu Weizhong, Zhu Zhu, Li Zheming, Xiao Rui, Shu Qiang, Yu Gang, Tao Ting

Abstract excerpt

BACKGROUND: Pediatric malignancies have emerged as the leading cause of disease-related mortality in children, exhibiting distinct etiological and molecular characteristics compared to adult cancers. Despite advances in genomic profiling, the molecular landscape of pediatric solid tumors, particularly in Chinese populations, remains undercharacterized. METHODS: Through targeted next-generation sequencing of 94...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomal Instability

Share to DNA Copy Number Variations

Share to Genomics

Share to High-Throughput Nucleotide Sequencing

Share to Infant

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41776381
DOI: 10.1002/cam4.71666
PMCID: PMC12956543

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative Genomic Profiling of Pediatric Solid Tumors Reveals Clinically Relevant Variants and Chromosomal Arm Aneuploidies Signatures.PMID 41776381Read ↗

Genomic Profiling of a Large Set of Diverse Pediatric Cancers Identifies Known and Novel Mutations across Tumor Spectra.Semantic proximity Read ↗

An update on genomic-guided therapies for pediatric solid tumors.Semantic proximity Read ↗

Molecular Alterations in Pediatric Solid Tumors.Semantic proximity Read ↗

Molecular genomic landscape of pediatric solid tumors in Chinese patients: Implications for clinical significanceSemantic proximity Read ↗

The genomic landscape of pediatric cancers: Implications for diagnosis and treatmentSemantic proximity Read ↗

Genomics-Driven Precision Medicine in Pediatric Solid TumorsSemantic proximity Read ↗

Mapping Genomic Heterogeneity in Pediatric and Adolescent-Young Adult Sarcomas: Insights from the Italian SAR-GEN2016 and SAR-GEN_ITA Prospective Multicenter Trials.Semantic proximity Read ↗

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.Semantic proximity Read ↗

SJPedPanel: A pan-cancer gene panel for childhood malignanciesSemantic proximity Read ↗

Genomic alterations in pediatric tumors: clinical relevance and translational insightsSemantic proximity Read ↗

Novel amplifications in pediatric medulloblastoma identified by genome-wide copy number profiling.Semantic proximity Read ↗

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.