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Article

Heme Oxygenase-1 Influences Satellite Cells and Progression of Duchenne Muscular Dystrophy in Mice.

Antioxidants & redox signaling - 10 Jul 2018

Pietraszek-Gremplewicz Katarzyna, Kozakowska Magdalena, Bronisz-Budzynska Iwona, Ciesla Maciej, Mucha Olga, Podkalicka Paulina, Madej Magdalena, Glowniak Urszula, Szade Krzysztof, Stepniewski Jacek, Jez Mateusz, Andrysiak Kalina, Bukowska-Strakova Karolina, Kaminska Anna, Kostera-Pruszczyk Anna, Jozkowicz Alicja, Loboda Agnieszka, Dulak Jozef

Abstract excerpt

AIMS: Muscle damage in Duchenne muscular dystrophy (DMD) caused by the lack of dystrophin is strongly linked to inflammation. Heme oxygenase-1 (HO-1; Hmox1) is an anti-inflammatory and cytoprotective enzyme affecting myoblast differentiation by inhibiting myomiRs. The role of HO-1 has not been so far well addressed in DMD. RESULTS: In dystrophin-deficient mdx mice, expression of Hmox1 in limb skeletal muscles and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29669436
DOI: 10.1089/ars.2017.7435

Genes

DMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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