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Article

Dlk1-Dio3 cluster miRNAs regulate mitochondrial functions in Duchenne muscular dystrophy

2021-10-20

Abstract excerpt

<h4>Background</h4> Duchenne Muscular Dystrophy (DMD) is a severe muscle disease caused by impaired expression of dystrophin. While mitochondrial dysfunction is thought to play an important role in DMD, the mechanism of this dysfunction remains to be clarified. We recently identified in DMD and in other muscular dystrophies the upregulation of a large number of the Dlk1-Dio3 clustered miRNAs (DD-miRNAs), in both...

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Literature Corpus work
e2db184e-9af6-5a7c-bc91-be0a3f04432c
DOI
10.1101/2021.10.20.464950
Open publication

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Dlk1-Dio3 cluster miRNAs regulate mitochondrial functions in Duchenne muscular dystrophyDOI 10.1101/2021.10.20.464950
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