Article

In dystrophic <i>mdx</i> hindlimb muscles where fibrosis is limited versican haploinsufficiency transiently improves contractile function without decreasing inflammation

2024-05-10

Abstract excerpt

<h4>ABSTRACT</h4> The provisional matrix protein versican is upregulated in Duchenne muscular dystrophy. Versican heightens inflammation in fibrotic diseases and is involved in myogenesis. In fibrotic diaphragm muscles from dystrophic mdx mice, versican reduction attenuated macrophage infiltration and improved contractile function. We investigated the association between versican and mdx hindlimb muscle patholo...

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Literature Corpus work: bf8f0662-be51-5036-9251-d17b88bd7673
DOI: 10.1101/2024.05.07.592907

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In dystrophic <i>mdx</i> hindlimb muscles where fibrosis is limited versican haploinsufficiency transiently improves contractile function without decreasing inflammationDOI 10.1101/2024.05.07.592907Read

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