Clustering of motor and nonmotor traits in leucine-rich repeat kinase 2 G2019S Parkinson's disease nonparkinsonian relatives: A multicenter family study.

doi:10.1002/mds.27272

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Article

Clustering of motor and nonmotor traits in leucine-rich repeat kinase 2 G2019S Parkinson's disease nonparkinsonian relatives: A multicenter family study.

Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2018

Mestre Tiago A, Pont-Sunyer Claustre, Kausar Farah, Visanji Naomi P, Ghate Taneera, Connolly Barbara S, Gasca-Salas Carmen, Kern Drew S, Jain Jennifer, Slow Elizabeth J, Faust-Socher Achinoam, Kasten Meike, Wadia Pettarusp M, Zadikoff Cindy, Kumar Prakash, de Bie Ronald M, Thomsen Teri, Lang Anthony E, Schüle Birgitt, Klein Christine, Tolosa Eduardo, Marras Connie

Abstract excerpt

OBJECTIVES: The objective of this study was to determine phenotypic features that differentiate nonparkinsonian first-degree relatives of PD leucine-rich repeat kinase 2 (LRRK2) G2019S multiplex families, regardless of carrier status, from healthy controls because nonparkinsonian individuals in multiplex families seem to share a propensity to present neurological features. METHODS: We included nonparkinsonian...

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PMID: 29665080
DOI: 10.1002/mds.27272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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