Article
Phenotype in parkinsonian and nonparkinsonian LRRK2 G2019S mutation carriers.
Neurology - 26 Jul 2011
Marras C, Schüle B, Schuele B, Munhoz R P, Rogaeva E, Langston J W, Kasten M, Meaney C, Klein C, Wadia P M, Lim S-Y, Chuang R S-I, Zadikof C, Steeves T, Prakash K M, de Bie R M A, Adeli G, Thomsen T, Johansen K K, Teive H A, Asante A, Reginold W, Lang A E
Abstract excerpt
OBJECTIVES: Using a family study design, we describe the motor and nonmotor phenotype in probands with LRRK2 G2019S mutations and family members and compare these individuals to patients with idiopathic Parkinson disease (iPD) and unrelated controls. METHODS: Probands with G2019S mutations and their first-degree relatives, subjects with iPD, and unrelated control subjects were identified from 4 movement disorders...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.