Article
Motor and non-motor features of Parkinson's disease in LRRK2 G2019S carriers versus matched controls.
Journal of the neurological sciences - 15 May 2018
Gunzler Steven A, Riley David E, Chen Shu G, Tatsuoka Curtis M, Johnson William M, Mieyal John J, Walter Ellen M, Whitney Christina M, Feng I Jung, Owusu-Dapaah Harry, Mittal Shivam O, Wilson-Delfosse Amy L
Abstract excerpt
INTRODUCTION: LRRK2 G2019S mutation carriers with Parkinson's disease (PD) have been generally indistinguishable from those with idiopathic PD, with the exception of variable differences in some motor and non-motor domains, including cognition, gait, and balance. LRRK2 G2019S is amongst the most common genetic etiologies for PD, particularly in Ashkenazi Jewish (AJ) populations. METHODS: This cross-sectional data...
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