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Article

Characterising the phenotypic evolution of circulating tumour cells during treatment.

Nature communications - 16 Apr 2018

Tsao Simon Chang-Hao, Wang Jing, Wang Yuling, Behren Andreas, Cebon Jonathan, Trau Matt

Abstract excerpt

Real-time monitoring of cancer cells' phenotypic evolution during therapy can provide vital tumour biology information for treatment management. Circulating tumour cell (CTC) analysis has emerged as a useful monitoring tool, but its routine usage is restricted by either limited multiplexing capability or sensitivity. Here, we demonstrate the use of antibody-conjugated and Raman reporter-coated gold nanoparticles...

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Identifiers

PMID: 29662054
DOI: 10.1038/s41467-018-03725-8
PMCID: PMC5902511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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