Article
Systematic classification of melanoma cells by phenotype-specific gene expression mapping.
Pigment cell & melanoma research - 1 May 2012
Widmer Daniel S, Cheng Phil F, Eichhoff Ossia M, Belloni Benedetta C, Zipser Marie C, Schlegel Natalie C, Javelaud Delphine, Mauviel Alain, Dummer Reinhard, Hoek Keith S
Abstract excerpt
There is growing evidence that the metastatic spread of melanoma is driven not by a linear increase in tumorigenic aggressiveness, but rather by switching back and forth between two different phenotypes of metastatic potential. In vitro these phenotypes are respectively defined by the characteris...
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