Article
Enabling Sensitive Phenotypic Profiling of Cancer-Derived Small Extracellular Vesicles Using Surface-Enhanced Raman Spectroscopy Nanotags.
ACS sensors - 27 Mar 2020
Zhang Wei, Jiang Lianmei, Diefenbach Russell J, Campbell Douglas H, Walsh Bradley J, Packer Nicolle H, Wang Yuling
Abstract excerpt
Circulating cancer-derived small extracellular vesicles (EVs) are nanoscale membranous vesicles shed from cancer cells that are released into surrounding body fluids. Small EVs contain biomolecules associated with cancer such as DNA and proteins for cell-to-cell communication. Therefore, small EVs have been regarded as important cancer biomarkers for liquid biopsy-based cancer diagnosis and drug treatment...
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