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Detection and prognostic role of heterogeneous populations of melanoma circulating tumour cells

10 Feb 2020

Abstract excerpt

BACKGROUND: Circulating tumour cells (CTCs) can be assessed through a minimally invasive blood sample with potential utility as a predictive, prognostic and pharmacodynamic biomarker. The large heterogeneity of melanoma CTCs has hindered their detection and clinical application. METHODS: Here we compared two microfluidic devices for the recovery of circulating melanoma cells. The presence of CTCs in 43 blood...

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PMID: 32037400
DOI: 10.1038/s41416-020-0750-9

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