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Simultaneous single-cell phenotype analysis of hepatocellular carcinoma CTCs using a SERS-aptamer based microfluidic chip.

Lab on a chip - 12 Oct 2021

Gao Rongke, Zhan Changbiao, Wu Chunyu, Lu Yang, Cao Baoqiang, Huang Jing, Wang Feng, Yu Liandong

Abstract excerpt

Hepatocellular carcinoma (HCC) is a harmful malady that truly debilitates human health, and hence it is of significance to isolate and on-line profile the phenotype of HCC cells for further diagnosis and therapy. We developed a novel strategy for efficient capture and in situ heterogeneous phenotype analysis of circulating tumor cells (CTCs) at the single-cell level based on surface-enhanced Raman scattering...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplastic Cells, Circulating

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Identifiers

PMID: 34387639
DOI: 10.1039/d1lc00516b

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