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In Situ Single Cell Proteomics Reveals Circulating Tumor Cell Heterogeneity during Treatment

6 Jul 2021

Abstract excerpt

Cancer is a dynamic disease with heterogenic molecular signatures and constantly evolves during the course of the disease. Single cell proteomic analysis could offer a suitable pathway to monitor cancer cell heterogeneity and deliver critical information for the diagnosis, recurrence, and drug-resistant mechanisms in cancer. Current standard techniques for proteomic analysis such as ELISA, mass spectrometry, and...

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PMID: 34225455
DOI: 10.1021/acsnano.0c10008

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