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Article

Cooperative behaviour and phenotype plasticity evolve during melanoma progression.

Pigment cell & melanoma research - 1 Sept 2020

Rowling Emily J, Miskolczi Zsofia, Nagaraju Raghavendar, Wilcock Daniel J, Wang Ping, Telfer Brian, Li Yaoyong, Lasheras-Otero Irene, Redondo-Muñoz Marta, Sharrocks Andrew D, Arozarena Imanol, Wellbrock Claudia

Abstract excerpt

A major challenge for managing melanoma is its tumour heterogeneity based on individual co-existing melanoma cell phenotypes. These phenotypes display variable responses to standard therapies, and they drive individual steps of melanoma progression; hence, understanding their behaviour is imperative. Melanoma phenotypes are defined by distinct transcriptional states, which relate to different melanocyte lineage...

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Source

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Identifiers

PMID: 32145051
DOI: 10.1111/pcmr.12873
PMCID: PMC7496243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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