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Article

Evaluation of high-fat high-fructose diet treatment in factor VIII (coagulation factor)-deficient mouse model.

International journal of experimental pathology - 1 Feb 2018

Mishra Alaknanda, Arindkar Shailendra, Sahay Preeti, Kumar Jerald Mahesh, Upadhyay Pramod K, Majumdar Subeer S, Nagarajan Perumal

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD)-like conditions enhance the production and action of clotting factors in humans. However, studies examining the effect of NAFLD due to high-fat high-fructose (HFHF) diet in factor VIII-deficient (haemophilia A) animals or patients have not been reported previously. In this study, we investigated the individual role of factor VIII in the progression of diet-induced NAFLD...

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Identifiers

PMID: 29656466
DOI: 10.1111/iep.12264
PMCID: PMC5917390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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