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Article

Analysis of neuroanatomical differences in mice with genetically modified serotonin transporters assessed by structural magnetic resonance imaging.

Molecular autism - 1 Jan 2018

Ellegood Jacob, Yee Yohan, Kerr Travis M, Muller Christopher L, Blakely Randy D, Henkelman R Mark, Veenstra-VanderWeele Jeremy, Lerch Jason P

Abstract excerpt

Background: The serotonin (5-HT) system has long been implicated in autism spectrum disorder (ASD) as indicated by elevated whole blood and platelet 5-HT, altered platelet and brain receptor and transporter binding, and genetic linkage and association findings. Based upon work in genetically modified mice, 5-HT is known to influence several aspects of brain development, but systematic neuroimaging studies have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29651330
DOI: 10.1186/s13229-018-0210-z
PMCID: PMC5894125

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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