Article
In vivo characterization of brain morphometric and metabolic endophenotypes in three inbred strains of mice using magnetic resonance techniques.
Behavior genetics - 1 Sept 2006
Penet Marie-France, Laigle Christophe, Fur Yann Le, Confort-Gouny Sylviane, Heurteaux Catherine, Cozzone Patrick J, Viola Angèle
Abstract excerpt
C57BL6J, FVB/N and 129/SvJ mice are commonly used as background strains to engineer genetic models of brain pathologies and psychiatric disorders. Magnetic resonance imaging (MRI) and spectroscopy provide alternative approaches to neuroanatomy, histology and neurohistochemistry for investigating the correlation between genes and brain neuroanatomy and neurometabolism in vivo. We used these techniques to...
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