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Article

Regional brain volumes changes in adult male FMR1-KO mouse on the FVB strain.

Neuroscience - 24 Mar 2016

Lai J K Y, Lerch J P, Doering L C, Foster J A, Ellegood J

Abstract excerpt

Fragile X Syndrome (FXS) is the most common heritable single gene cause of autism spectrum disorder (ASD). FMR1-KO mice mimic the etiology and phenotypic manifestations of FXS. Neuroanatomical changes in specific brain regions have been reported in clinical settings and in preclinical models. FMR1-KO mice have been generated in different strains including C57Bl/6 (B6) and FVB. Mice on different genetic...

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Source

Identifiers

PMID: 26794591
DOI: 10.1016/j.neuroscience.2016.01.021

Genes

FMR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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