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Article

The complex role of genetic background in shaping the effects of spontaneous and induced mutations.

Yeast (Chichester, England) - 1 Mar 2021

Goldstein Ilan, Ehrenreich Ian M

Abstract excerpt

Spontaneous and induced mutations frequently show different phenotypic effects across genetically distinct individuals. It is generally appreciated that these background effects mainly result from genetic interactions between the mutations and segregating loci. However, the architectures and molecular bases of these genetic interactions are not well understood. Recent work in a number of model organisms has tried...

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Identifiers

PMID: 33125810
DOI: 10.1002/yea.3530
PMCID: PMC7984271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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