Article
Promoting Myelin Repair through In Vivo Neuroblast Reprogramming.
Stem cell reports - 8 May 2018
El Waly Bilal, Cayre Myriam, Durbec Pascale
Abstract excerpt
Demyelination is frequently observed in a variety of CNS insults and neurodegenerative diseases. In rodents, adult neural stem cells can generate oligodendrocytes and participate to myelin repair. However, these cells mainly produce migratory neuroblasts that differentiate in the olfactory bulb. Here, we show that, in the demyelination context, a small subset of these neuroblasts can spontaneously convert into...
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