Article

Human glial progenitor cells effectively remyelinate the demyelinated adult brain

2019-10-31

Abstract excerpt

<h4>ABSTRACT</h4> Human glial progenitor cells (hGPCs) can completely myelinate the brains of congenitally hypomyelinated shiverer mice, rescuing the phenotype and extending or normalizing the lifespan of these mice. We asked if implanted hGPCs might be similarly able to broadly disperse and remyelinate the diffusely and/or multicentrically-demyelinated adult CNS. In particular, we asked if fetal hGPCs could eff...

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Literature Corpus work: b591875b-2f37-53b0-b9df-a005734afa0e
DOI: 10.1101/822494

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