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Article

Effects of ceftriaxone on hydrocodone seeking behavior and glial glutamate transporters in P rats.

Behavioural brain research - 16 Jul 2018

Alshehri Fahad S, Hakami Alqassem Y, Althobaiti Yusuf S, Sari Youssef

Abstract excerpt

Hydrocodone (HYD) is one of the most widely prescribed opioid analgesic drugs. Several neurotransmitters are involved in opioids relapse. Among these neurotransmitters, glutamate is suggested to be involved in opioid dependence and relapse. Glutamate is regulated by several glutamate transporters, including glutamate transporter 1 (GLT-1) and cystine/glutamate transporter (xCT). In this study, we investigated the...

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Source

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Identifiers

PMID: 29604365
DOI: 10.1016/j.bbr.2018.03.043
PMCID: PMC5988953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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