Article
Genetic differences in the modulation of accumbal glutamate and γ-amino butyric acid levels after cocaine-induced reinstatement.
Addiction biology - 1 Jul 2013
Miguéns Miguel, Botreau Fanny, Olías Oscar, Del Olmo Nuria, Coria Santiago M, Higuera-Matas Alejandro, Ambrosio Emilio
Abstract excerpt
The Lewis (LEW) and Fischer 344 (F344) inbred rat strains are frequently used to study the role of genetic factors in vulnerability to drug addiction and relapse. Glutamate and γ-amino butyric acid (GABA) transmission are significantly altered after cocaine-induced reinstatement, although whether...
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