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Article

Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5).

PloS one - 30 Nov 2010

Olsen Christopher M, Childs Daniel S, Stanwood Gregg D, Winder Danny G

Abstract excerpt

Pharmacological and genetic studies have suggested that the metabotropic glutamate receptor 5 (mGluR5) is critically involved in mediating the reinforcing effects of drugs of abuse, but not food. The purpose of this study was to use mGluR5 knockout (KO), heterozygous (Het), and wildtype (WT) mice...

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Source

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Identifiers

PMID: 21152045
DOI: 10.1371/journal.pone.0015085
PMCID: PMC2994905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21152045-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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