Article
d-Cycloserine enhanced extinction of cocaine-induced conditioned place preference is attenuated in serotonin transporter knockout rats.
Addiction biology - 1 Jan 2018
Karel Peter, Calabrese Francesca, Riva Marco, Brivio Paola, Van der Veen Bas, Reneman Liesbeth, Verheij Michel, Homberg Judith
Abstract excerpt
d-Cycloserine (DCS), a partial NMDA receptor agonist, has been proposed as a cognitive enhancer to facilitate the extinction of drug-related memories. However, it is unknown whether there are individual differences in the efficacy of DCS. Here, we set out to investigate the influence of serotonin transporter (5-HTT) genotype on DCS treatment outcome and the underlying neural mechanism. To that end, we first...
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