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Article

Identification of Proteins Required for Precise Positioning of Apc2 in Dendrites.

G3 (Bethesda, Md.) - 4 May 2018

Weiner Alexis T, Seebold Dylan Y, Michael Nick L, Guignet Michelle, Feng Chengye, Follick Brandon, Yusko Brandon A, Wasilko Nathan P, Torres-Gutierrez Pedro, Rolls Melissa M

Abstract excerpt

In Drosophila neurons, uniform minus-end-out polarity in dendrites is maintained in part by kinesin-2-mediated steering of growing microtubules at branch points. Apc links the kinesin motor to growing microtubule plus ends and Apc2 recruits Apc to branch points where it functions. Because Apc2 acts to concentrate other steering proteins to branch points, we wished to understand how Apc2 is targeted. From an...

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Identifiers

PMID: 29602811
DOI: 10.1534/g3.118.200205
PMCID: PMC5940173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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