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Article

Slit and Robo control the development of dendrites in Drosophila CNS.

Development (Cambridge, England) - 1 Nov 2007

Furrer Marie-Pierre, Vasenkova Irina, Kamiyama Daichi, Rosado Yaira, Chiba Akira

Abstract excerpt

The molecular mechanisms that generate dendrites in the CNS are poorly understood. The diffusible signal molecule Slit and the neuronally expressed receptor Robo mediate growth cone collapse in vivo. However, in cultured neurons, these molecules promote dendritic development. Here we examine the aCC motoneuron, one of the first CNS neurons to generate dendrites in Drosophila. Slit displays a dynamic concentration...

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Source

Identifiers

PMID: 17933790
DOI: 10.1242/dev.02882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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