Article
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings.
PLoS genetics - 1 Mar 2006
Visscher Peter M, Medland Sarah E, Ferreira Manuel A R, Morley Katherine I, Zhu Gu, Cornes Belinda K, Montgomery Grant W, Martin Nicholas G
Abstract excerpt
The study of continuously varying, quantitative traits is important in evolutionary biology, agriculture, and medicine. Variation in such traits is attributable to many, possibly interacting, genes whose expression may be sensitive to the environment, which makes their dissection into underlying causative factors difficult. An important population parameter for quantitative traits is heritability, the proportion...
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