Article

Recovery of trait heritability from whole genome sequence data

2019-03-25

Abstract excerpt

Heritability, the proportion of phenotypic variance explained by genetic factors, can be estimated from pedigree data 1 , but such estimates are uninformative with respect to the underlying genetic architecture. Analyses of data from genome-wide association studies (GWAS) on unrelated individuals have shown that for human traits and disease, approximately one-third to two-thirds of heritability is captured by com...

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Literature Corpus work: 9d3101c0-a395-50c8-b57a-806bd4dd61d2
DOI: 10.1101/588020

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