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Article

Associations of ICOS and PD.1 Gene Variants with Colon Cancer Risk in The Iranian Population

Asian Pacific journal of cancer prevention : APJCP - 27 Mar 2018

Shamsdin Seyedeh Azra, Karimi Mohammad Hossein, Hosseini Seyed Vahid, Geramizadeh Bita, Fattahi Mohamad Reza, Mehrabani Davood, Moravej Ali

Abstract excerpt

Background: Positive and negative co-stimulatory molecules are important factors determining the outcome of immune responses to the presence of tumors. Since co-stimulatory molecule expression may be affected by gene polymorphisms, we aimed to investigate associations between variants of PD.1 and ICOS and susceptibility to colon cancer. Material and methods: ICOS (-693A/G), ICOS (+1720C/T) and PD.1 (-538G/A) gene...

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Identifiers

PMID: 29580042
DOI: 10.22034/APJCP.2018.19.3.693
PMCID: PMC5980843

Genes

ICOS
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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